Neurohumoral Transmission in CNS: GABA, Glutamate & More
Neurohumoral Transmission in the CNS: Role of Key Neurotransmitters (GABA, Glutamate, Glycine, Serotonin, Dopamine) Neurohumoral transmission in the CNS is one of the most high-yield topics for GPAT, university pharmacology exams, and allied health entrance tests. Understanding how chemical messengers like GABA, glutamate, glycine, serotonin, and dopamine work at the synapse is the foundation of modern neuropharmacology — and the key to understanding how most CNS drugs work. In this blog, we break down the entire concept from basics to clinical application — with mnemonics, comparison tables, Canva diagram placeholders, and exam pearls. Let's get started! 🧠📚 Table of Contents What is Neurohumoral Transmission? Steps of Chemical Synaptic Transmission in CNS Major Neurotransmitters in the CNS Glutamate – The Primary Excitatory Neurotransmitter GABA – The Main Inhibitory Neurotransmitter Glycine – Inhibitory Control in the Spinal Cord Serotonin – ...